Symbol
Name
ID

Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
MGI:1100842

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

nervous system phenotype

abnormal neuronal precursor proliferation

abnormal muscle spindle morphology

abnormal nervous system morphology

abnormal enteric nervous system morphology

abnormal enteric ganglia morphology

abnormal enteric neuron morphology

absent enteric neurons

abnormal parasympathetic system morphology

abnormal otic ganglion morphology

abnormal pterygopalatine ganglion morphology

abnormal innervation pattern to muscle

abnormal motor neuron innervation pattern

abnormal nervous system development

loss of dopaminergic neurons

abnormal motor neuron morphology

decreased motor neuron number

abnormal somatic nervous system morphology

small petrosal ganglion

abnormal nodose ganglion morphology

abnormal trigeminal nerve morphology

abnormal spinal nerve morphology

abnormal spinal cord lateral motor column morphology

abnormal neurotransmitter secretion

Availability

Mouse Genotype

Gfra1^tm1Bjh/Gfra1^tm1Bjh

Gfra1^tm1Jmi/Gfra1^tm1Jmi

Gfra1^tm1Rosl/Gfra1^tm1Rosl

Gfra1^tm2.1Jmi/Gfra1^tm2.1Jmi

Gfra1^tm3Jmi/Gfra1^tm3Jmi

Gfra1^tm1Jmi/Gfra1⁺

Gfra1^tm2Jmi/Gfra1^tm2Jmi
Mnx1^tm4(cre)Tmj/Mnx1⁺ (conditional)

Gfra1^tm1Jmi/Gfra1^tm2Jmi
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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